PCOD (Poly-Cystic Ovarian Disease) is a disease characterized by multiple cysts (small sacs filled with fluid) in the ovaries. “Poly” means many. The patient usually presents with history of irregular menstrual cycles; unpredictable and heavy. The patient is often obese and has hirsutism (excessive facial and body hair). The patient usually seeks medical opinion for difficulty in conceiving. Various hormones of the body are working in harmony to regularize smooth functioning of reproductive system. The disturbance of hormonal mechanism make an ovary to produce excessive amount of reproductive hormone and at the same time there is failure of egg formation. This excess with absence of ovulation may cause infertility. With this understanding that the disturbed hormonal functioning of the body at the root of PCOD, it can be easily perceived that this constitutional disorder will require constitutional approach towards its rectification. Homoeopathy approach towards management of PCOD is constitutional, taking into account presenting complaints along with physical, mental, and genetic make up that individualizes a person. Homoeopathy medicines which act at root level can bring back deviations of hormonal system back to normalcy and in many cases abolish need of exogenous hormones with their side effects and complicating surgical procedures. Moreover with this hormonal harmony, chances of conception increase significantly.